Czech 
Slovenčina 
Română 
Polski 
Español 
Français 
Italiano 
Magyar 
English 
Deutsch
10% discount if you order while logged in. Login
Notify me when we upload a product like this:
| Country: | Hungary (Europe) |
| Series: | Engineers, Inventors |
| Topic: | Hungarian invention serving as the basis of mRNA-based vaccines |
| Type: | Commemorative |
| Note: | 2022 |
| Denomination: | 15000 Forint |
| Composition: | Silver 925 |
| Weight: | 31,46 g |
| Silver content: | 28.675 g (92.5%) |
| Diameter: | 38,61 mm |
| Obverse: | Az emlékérmék előlapján két módosított messenger (hírvivő) ribonukleinsav molekula (mRNS) spirál stilizált ábrázolása jelenik meg központi motívumként, mely alatt öt egymás alatti sorban találhatóak az emlékérmék kötelező elemei: a kibocsátót megjelenítő „MAGYARORSZÁG” felirat, a „15000”, illetve „3000” értékjelzés, a „FORINT” felirat, a „2022” verési évszám, valamint a „BP.” verdejel. |
| Reverse: | A hátlap központi motívuma egy nukleozid-módosított mRNS lipid nanopartikulát, azaz egy zsírrészecskét ábrázol, ami magában foglalja a módosított mRNS spirálokat. Az mRNS spirálok kinagyítva, a zsírrészecske mellett láthatóak. A találmány lényege, hogy a terápiás célú mRNS biztonságosan jusson a szervezetbe, hatékonyan lássa el a feladatát, ezért zsírmolekulába, ún. lipid nanopartikulába csomagolták az RNS-t. Alattuk két egymás alatti sorban a „nukleozid-módosított mRNS lipid nanopartikula” felirat olvasható. A felirat alatt egy mRNS spirál stilizált ábrázolása, alatta az emlékérmét tervező Szilos András iparművész mesterjegye látható. A hátlap szélén – egy-egy ponttal elválasztva, az óramutató járásával megegyezően – az mRNS-alapú vakcinák kutatásában kiemelkedő szerepet játszó tudósok neve - „KARIKÓ KATALIN”, „IAN MACLACHLAN”, „PARDI NORBERT”, „DREW WEISSMAN” - olvasható. |
| Edge: | Plain |
| Description: | Today, the Magyar Nemzeti Bank is issuing commemorative coins with a nominal value of HUF 15,000 and non-ferrous metals with a nominal value of HUF 3,000 with the name "Hungarian invention serving as the basis for mRNA-based vaccines" at the University of Szeged. The square-shaped commemorative coins designed by the industrial artist András Szilos and placed on top present the essence of the invention, naming the Hungarian, American and Canadian scientists who played a prominent role in the research. In the protection against the SARS-CoV-2 virus and in the suppression of the worldwide epidemic that broke out in 2020, messenger RNA (messenger RNA, mRNA)-based vaccines against COVID-19 infection play a significant role, the development of which was based on the collaboration of many researchers. Two Hungarian scientists stand out among them, Katalin Karikó and Norbert Pardi. It is thanks to the former that the introduction of the mRNA molecule into the body became safe, and to the latter, that the instability of the mRNA was eliminated by wrapping it in a fat molecule, and the introduction of the mRNA into the cells became efficient. Based on the research of the last decades, it was found that the synthetically produced mRNA coding for viral proteins injected into the human body can also provide protection against various viral infections. The cells prepare the required section of the foreign virus protein from the mRNA, and then, in response, our immune system produces antibodies (and often other special immune cells) with which the body can fight the virus. The mRNA molecules coding for viral proteins are perceived as foreign substances by the cells of the body, but thanks to the modification, it was possible to perform its therapeutic tasks safely and effectively. This success lays the foundation for further mRNA-based vaccine development against important pathogens such as influenza virus, herpes virus and HIV. Furthermore, many new fields of application are opened by using mRNA-based agents, such as the treatment of incurable diseases by gene editing, the development of a vaccine against cancer. The development and testing of the two main components of the vaccine platform (nucleoside-modified mRNA and the carrier lipid nanoparticle) is the result of several decades of persistent research. The Magyar Nemzeti Bank issues a silver commemorative coin with a nominal value of HUF 15,000, as well as a non-ferrous metal version with a nominal value of HUF 3,000, as a tribute to the results and persistent work of the participants in the research. The primary role of commemorative coins is to attract attention, they do not play a role in cash circulation. The images of the silver and non-ferrous commemorative coins are the same, they differ only in the denomination. Source: MNB |
| Engraver: | Szilos András |
| Motif: | Invention, Katalin Kariko |